Season 5

E1. Julie Bowen / Jonathan Winters / Priscilla Ahn

Sep 1, 2008 · 60m

E2. Katey Sagal / Nathan Fillion

Sep 2, 2008 · 60m

E3. Julie Chen / Maria Bello / Shelby Lynne

Sep 3, 2008 · 60m

E4. Eva Longoria / Neal McDonough

Sep 4, 2008 · 60m

E5. Kal Penn / Gabe Dixon Band

Sep 5, 2008 · 60m

E6. Julie Chen / Neil Patrick Harris / Sophia Myles

Sep 8, 2008 · 60m

Craig welcomes TV host Julie Chen for a "Big Brother" update, actor Neil Patrick Harris and actress Sophia Myles.

E7. Russell Brand / Margaret Cho

Sep 9, 2008 · 60m

E8. Alice Cooper / AnnaLynne McCord

Sep 10, 2008 · 60m

E9. Lynn Ferguson / Lance Morrow

Sep 11, 2008 · 60m

Craig welcomes his sister, actress Lynn Ferguson and author Lance Morrow.

E10. Seann William Scott / Lena Heady

Sep 12, 2008 · 60m

Craig welcomes actress Lena Heady. Sean William Scott is stuck in traffic, so he welcomes segment producer Lisa Ammerman instead.

E11. Julie Chen / Jason Biggs / The Ting Tings

Sep 15, 2008 · 60m

E12. Paulina Porizkova / Ken Tucker / Tally Hall

Sep 16, 2008 · 60m

E13. Alan Alda / Illeana Douglas

Sep 17, 2008 · 60m

E14. Jason Segel / Dr Dog / Steve Hofstetter

Sep 18, 2008 · 60m

E15. Kristen Bell / Josh Radnor

Sep 19, 2008 · 60m

Craig welcomes actress Kristen Bell, actor Josh Radnor. With special feature of "Murder, She Wrote" with Samuel L. Jackson.

E16. Denis Leary / Marianne Jean-Baptiste

Sep 22, 2008 · 60m

E17. John Krasinski / Lisa Masterson

Sep 23, 2008 · 60m

E18. Michael Clarke Duncan / Shirley Manson / Jamie Lidell

Sep 24, 2008 · 60m

E19. Tim Gunn / Elizabeth Reaser

Sep 25, 2008 · 60m

E20. Drew Carey / Tony Parker / Lady Antebellum

Sep 26, 2008 · 60m

E21. Melina Kanakaredes / Gina Carano / Amy Macdonald

Sep 29, 2008 · 60m

E22. Tim Daly / Anna Friel / Alice Cooper

Sep 30, 2008 · 60m

E23. Jennifer Love Hewitt / Jim Parsons

Oct 1, 2008 · 60m

E24. Lauren Graham / Patrick Pedraja / Michael Franti & Spearhead

Oct 2, 2008 · 60m

E25. Margaret Cho / Randy Newman / Randy Newman

Oct 3, 2008 · 60m

E26. Seth Green / Betty White / Smothers Brothers

Oct 6, 2008 · 60m

E27. Thandie Newton / Barry Sonnenfeld / Jim Bianco

Oct 7, 2008 · 60m

Craig welcomes actress Thandie Newton and director Barry Sonnenfeld. Musical Guest Jim Bianco performs "I Got A Thing For You".

E28. Rufus Sewell / Natasha Bedingfield

Oct 8, 2008 · 60m

E29. Russell Crowe / Jennifer Esposito

Oct 9, 2008 · 60m

E30. Matt Lucas & David Walliams / Tom Morello

Oct 10, 2008 · 60m