Season 4

2010

Jan 4, 2010 · 30m

We're starting off the new year with Robin Thicke and his Sex Therapy...like father like son. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Guy Branum are on the panel.

E2. Mary J. Blige

Jan 5, 2010 · 30m

We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

E3. Holly Madison

Jan 6, 2010 · 30m

We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

E4. Joel David Moore

Jan 7, 2010 · 30m

Holly Madison is dropping on by her old E! family today...we've missed her, too. Comedian Donnel Rawlings, comedian Heather McDonald and comedian Gary Valentine.

E5. Giuliana & Bill Rancic

Jan 11, 2010 · 30m

Word on the street is Giuliana and Bill Rancic are trying to have a baby. What're the odds that we'll get any sort of big announcement? Comedian Brad Wollack, comedian Natasha Leggero and comedian Matt Braunger.

E6. Aisha Tyler

Jan 12, 2010 · 30m

We welcome back the very funny Aisha Tyler, from the new show Archer. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.

E7. Amy Brenneman

Jan 13, 2010 · 30m

Amy Brenneman of Private Practice stops by, perhaps with some doctorly advice. Comedian John Caparulo, comedian Jen Kirkman and comedian Dan Levy.

E8. Snooki, Pauly D and The Situation

Jan 14, 2010 · 30m

Fist pumps all around for Jersey Shore's Snooki, Pauly D and The Situation. Comedian Chris Franjola, comedian Whitney Cummings and TV personality Ross Mathews.

E9. David Arquette

Jan 18, 2010 · 30m

David Arquette is back and telling us all about his new play The Female of the Species and the Golden Globes! Comedians Michelle Collins and Randy and Jason Sklar

E10. Adrianne Palicki

Jan 19, 2010 · 30m

Clear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's Tyra). Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Eric Price.

E11. Kaley Cuoco

Jan 20, 2010 · 30m

Who wouldn't be stoked that Kaley Cuoco from the megapopular Big Bang Theory is here? Comedian Heather McDonald, TV personality Ross Mathews and comedian Lavell Crawford.

E12. James Van Der Beek

Jan 21, 2010 · 30m

James Van Der Beek is in the new movie Formosa Betrayed and popping up all over TV—even here! E!'s own Michael Yo, comedian Sarah Colonna and comedian Guy Branum.

E13. Katharine McPhee

We're beyond pleased to welcome back our animal guy Dave Salmoni and his new animal friends. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Mo Mandel.

We get down to business with The Office's Kate Flannery. Comedian Loni Love, comedian Dan Levy and comedian Whitney Cummings.

E26. Jackie Collins

Feb 16, 2010 · 30m

Things get really scandalous when author Jackie Collins stops by with her new book, Poor Little Bitch Girl. Comedian Chris Hardwick, comedian Jen Kirkman and comedian Jo Koy.

E27. Lisa Edelstein

Feb 17, 2010 · 30m

Lisa Edelstein from House is back again...Wait, so who's running Princeton Plainsboro? Comedian Josh Wolf, comedian Heather McDonald and comedian Ryan Stout.

E28. Eli Roth

Feb 18, 2010 · 30m

E29. Keshia Knight Pulliam

Feb 22, 2010 · 30m

House of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable would be so proud. Comedian Loni Love, TV personality Rove McManus and comedian Michelle Collins

E30. Danica Patrick

Feb 23, 2010 · 30m

We're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea Lately today. Comedian Josh Wolf, comedian Whitney Cummings and comedian Jo Koy.