Steve Carell

Gru / Dru (voice)

Kristen Wiig

Lucy Wilde (voice)

Trey Parker

Balthazar Bratt (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier

Edith (voice)

Nhev Scharrel

Agnes (voice)

Pierre Coffin

Mel / Minions / Museum Director / Additional Voice (voice)

Steve Coogan

Fritz / Silas Ramsbottom (voice)

Julie Andrews

Gru’s Mom (voice)

Jenny Slate

Valerie Da Vinci (voice)

Michael Beattie

Scar-Faced Man / TMZ Announcer (voice)

Andy Nyman

Clive the Robot (voice)

Adrian Ciscato

Niko (voice)

Brian T. Delaney

Commercial Announcer / Military Officer / Additional Voice (voice)

Katia Saponenko

Niko’s Mother (voice)

Ken Daurio

Celebrity (voice)

Jude Alpers

Commercial Kid (voice)

Cory Walls

Vincenzo (voice)

Sophie M. Siadatpour

Little Girl (voice)

Lori Alan

Additional Voice (voice)

Carlos Alazraqui

Additional Voice (voice)

Kyle Balda

Additional Voice (voice)

Bob Bergen

Additional Voice (voice)

John Cygan

Additional Voice (voice)

Bill Farmer

Additional Voice (voice)